If you refresh the PG (maybe twice), the mute icon (shown in image below) stays until the user clicks on the page. Only after the user clicks on the page does the audio play.
My understanding is that this is a policy of Chrome (and other browsers) not to autoplay audio or video with sound until a user interaction on the page.
There may be fancy hacks/workarounds but you might be better off waiting for the first user interaction or soliciting an interaction.