I have found and fixed the root cause of React Dev tools blocking game load. And confirmed the fix works. Sorry for the long delay! 
I’m not sure if the fix pertains to your use case. If you can find time to try again, it would be great! If not, kindly drop me a pm/ss of your extensions. I can reproduce the problem and fix. Thanks! 
On 2nd thoughts …maybe a little share wouldn’t hurt. React dev tools browser extension inject a 'message' event listener at document start that conflicts with my web worker causing an infinite loop to trigger, effectively blocking the rest of the dependencies from loading. Moving the webworker to load via trusted types API solved the problem. So if anyone uses webworkers for bjs chores, I hope this little bug tracking helps. Cheers! 