Sure! It’s related to this thread : Gizmo use tmpParent but do not preserve scaling sign - #51 by Cedric
to make it short: a gizmo using a mesh in a hierarchy but the non uniform scaling is present in different nodes in the hierarchy. You can end up with a mesh having a scaling of 1,1,1 but a parent has -1.
This may happen to you with imported gltf in left hand coordinates and/or with more levels in the hierarchy.
non uniform negative scaling is hard to fix for all the use cases. keep me posted if you find more edge cases.